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    Research Summaries in Focus



    Summarized & Presented by:
    Mohammad Adnan Abu Khalifeh – BDS

    • Assistant Editor, Smile Dental Journal
    • e-communication Committee Vice President, JDA
    • Health Editor, UMEN MAGAZINE
    • Co-Owner, Dental Lounge/Smile Studio,
    Amman – Jordan | harper2003@gmail.com




    Clinical Performance of a Glass Ionomer Restorative System: a 6-year Evaluation

    Gurgan S, Kutuk ZB, Ergin E, Oztas SS, Cakir FY Clin Oral Investig. 2016 Dec 20. doi: 10.1007/s00784-016-2028-4. [Epub ahead of print]


    The aim of this study is to evaluate the long-term clinical performance of a glass ionomer (GI) restorative system in the restoration of posterior teeth compared with a micro-filled hybrid posterior composite.

    A total of 140 (80 Cl1 and 60 Cl2) lesions in 59 patients were restored with a GI system (Equia) or a micro hybrid composite (Gradia Direct). Restorations were evaluated at baseline and yearly during 6 years according to the modified-USPHS criteria. Negative replicas at each recall were observed under SEM to evaluate surface characteristics. Data were analyzed with Cohcran’s Q and McNemar’s tests (p < 0.05).

    One hundred fifteen (70 Cl1 and 45 Cl2) restorations were evaluated in 47 patients with a recall rate of 79.6% at 6 years. Significant differences were found in marginal adaptation and marginal discoloration for both restorative materials for Cl1 and Cl2 restorations (p < 0.05). However, none of the materials were superior to the other (p > 0.05). A significant decrease in color match was observed in Equia restorations (p < 0.05). Only one Cl2 Equia restoration was missing at 3 years and another one at 4 years. No failures were observed at 5 and 6 years. Both materials exhibited clinically successful performance after 6 years. SEM evaluations were in accordance with the clinical findings.

    Both materials showed a good clinical performance for the restoration of posterior teeth during the 6-year evaluation.

    The clinical effectiveness of Equia and Gradia Direct Posterior was acceptable in Cl1 and Cl2 cavities subsequent to 6-year evaluation.





    Could the Application of Bioactive Molecules Improve Vital Pulp Therapy Success? A Systematic Review


    de Oliveira da Rosa WL, da Silva TM, Demarco FF, Piva E, da Silva AF J Biomed Mater Res A. 2016 Dec 20. doi: 10.1002/jbm.a.35968. [Epub ahead of print]


    This study aimed to systematically review the literature of animal studies to evaluate whether bioactive dentin proteins could improve vital pulp therapy success. The review is reported in accordance with the PRISMA Statement. Two reviewers independently conducted a literature search of seven databases: PubMed (Medline), Lilacs, IBECS, BBO, Web of Science, Scopus and SciELO. Animal experiments in which bioactive dentin proteins were applied directly or indirectly to the pulp tissue were included. Data regarding the characteristics of the proteins evaluated, the delivery systems used and the main findings from each study were tabulated to assess the outcomes of interest
    (tertiary dentin formation, inflammatory response, intratubular mineralization). After screening, 32 papers were subjected to qualitative analysis. In 75% of the studies, direct pulp capping was performed. Additionally, the most studied proteins were BMP-7, TGF-ß1, and extracted soluble dentin matrix proteins. In conclusion, there is evidence in the literature suggesting that bioactive dentin molecules could enhance tertiary dentin formation with fewer initial inflammatory responses in direct and indirect pulp therapy in animal models. There are potential areas to be explored for novel therapeutic approaches for dental tissue repair and regeneration with bioactive materials. This article is protected by copyright. All rights reserved.







    Piezotome Rhinoplasty Reduces Postsurgical Morbidity and Enhances Patient Satisfaction: A Multidisciplinary Clinical Study


    Troedhan A.
    J Oral Maxillofac Surg. 2016 Aug;74(8):1659.e1-1659.e11


    Experimental and clinical studies in various fields of oral and maxillofacial surgery suggest the use of piezotomes to reduce postsurgical morbidity and enhance healing. The aim of the study was to investigate if rhinoplasty surgery with piezotomes might decrease postsurgical morbidity and increase overall patient satisfaction when compared with rhinoplasty with traditional instruments and protocols.


    In this prospective clinical study, patients in a cosmetic surgery department, ear-nose-throat (ENT) department, and the department for maxillofacial surgery, scheduled for cosmetic reductive rhinoplasty, underwent rhinoplasty with traditional instruments or an ultrasonic surgical device called a “piezotome.” Before rhinoplasty, all patients were evaluated by the Rhinoplasty Outcome Evaluation (ROE) questionnaire. Staging for ecchymosis/edema and for pain was performed on the seventh day after surgery, and at 6 months after surgery, patients were again evaluated by the ROE score. Female and male patients aged between 24 and 57 years were included; patients had to be free of functional impairments of nasal breathing. Data were anonymized and evaluated with SPSS software (version 22.0; IBM, Armonk, NY) (1-way analysis of variance, Games-Howell post hoc test for primary and secondary outcome evaluation, Levene test of equal variances, t test, and Pearson correlation of primary and secondary outcome evaluation).


    Eighty-four patients were fully documented by ecchymosis/ edema staging, pain staging, and ROE; of these, 51 women and 12 men underwent cosmetic rhinoplasty in a department of plastic and reconstructive surgery; an ENT department; or a department for maxillofacial surgery. A piezotome rhinoplasty was performed in 16 female and 5 male patients. Statistical evaluation verified that there were no significant differences between the three surgical disciplines when a rhinoplasty was performed with traditional instruments (P > .7), but showed that the use of ultrasonic surgical instruments significantly improved immediate postsurgical morbidity in terms of ecchymosis/ edema and pain (P < .05), as well as ROE score after 6 months (P < .05). Correlation of ecchymosis/edema and pain with ROE score showed a significant difference (P ≤ .01) in favor of the piezotome.


    The use of ultrasonic surgical devices in reductive rhinoplasty decreases postsurgical morbidity and increases overall patient satisfaction significantly. The results of this study suggest piezotomes to be the surgical instrument of choice not only for oral surgical procedures, but also for cosmetic surgery on facial bones.